From the MS Society of Ireland's pages....more information on the
history of the veins in MS. It has taken 140 years to find the answer to
venous congestion- in CCSVI.
"Further insight into the pathophysiology of MS was provided by Eduard Rindfleisch, a 19th century German pathologist, who analysed post-mortem brain samples from MS patients
In 1863, Rindfleisch reported a key finding that paved the way for theories of inflammatory involvement in the aetiology of MS. He noticed that, consistently in all the specimens, a blood vessel was present at the centre of each lesion. His illustrations of the plaques are seen in the slide.
Rindfleisch wrote:
"If one looks carefully at freshly altered parts of the white matter ... one perceives already with the naked eye a red point or line in the middle of each individual focus,.. the lumen of a small vessel engorged with blood ... All this leads us to search for the primary cause of the disease in an alteration of individual vessels and their ramifications; All vessels running inside the foci, but also those which traverse the immediately surrounding but still intact parenchyma are in a state characteristic of chronic inflammation."
"Further insight into the pathophysiology of MS was provided by Eduard Rindfleisch, a 19th century German pathologist, who analysed post-mortem brain samples from MS patients
In 1863, Rindfleisch reported a key finding that paved the way for theories of inflammatory involvement in the aetiology of MS. He noticed that, consistently in all the specimens, a blood vessel was present at the centre of each lesion. His illustrations of the plaques are seen in the slide.
Rindfleisch wrote:
"If one looks carefully at freshly altered parts of the white matter ... one perceives already with the naked eye a red point or line in the middle of each individual focus,.. the lumen of a small vessel engorged with blood ... All this leads us to search for the primary cause of the disease in an alteration of individual vessels and their ramifications; All vessels running inside the foci, but also those which traverse the immediately surrounding but still intact parenchyma are in a state characteristic of chronic inflammation."
